产品货号:
Z10028
中文名称:
AATF抗体
英文名称:
Anti-AATF Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AATF Antibody |
指标别名 | AATF;CHE 1;CHE1;DED;Protein AATF;Rb binding protein Che 1;Traube |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,IHC,WB |
基因名称 | AATF |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human Che-1 |
计算分子量 | 63KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Che-1,also known as AATF (apoptosis-antagonizing transcription factor),is a RNA polymerase II-binding protein involved in regulating the transcription factor E2F and promoting cell cycle progression (Burgdorf et al.,2004).It has been suggested that Che-1 may act as a neuroprotective factor against Abeta-induced apoptosis by suppressing the production of reactive oxidative species (Xie et al.,2004).The checkpoint kinase Chk2 has been shown to phosphorylate Che-1 at Ser-477 contributing to the maintenance of the G2/M checkpoint induced by DNA damage (Bruno et al.,2006). |
Uniprot ID | Q9NY61 |
基因名全称 | Protein AATF |
蛋白名全称 | Protein AATF |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 ELISA 1:10000 |
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